Arenax Forte (20/120)mg

Mechanism Of Action: Artemether and Lumenfantrine (AL) is an antimalarial, artemisin based combination. Artemether is an artemisin derivative. This metabolite undergoes cleavage of it’s endoperoxidase ring inside the erythrocytes. As the drug molecules come in contact with the harm, the Iron II oxide breaks the endoperoxidase ring. This produces free radicals that in turn damage susceptible proteins, resulting in the death of the parasite. Lumenfantrine which has a longer half life compared to artemether clears any residual parasites that remains after treatment. Dose: Adult & Child over 12yrs, with body weight over 35kg, AL as fixed dose is given by mouth twice daily for 3 days, with the 2nd dose given 8hrs after the 1st dose. 5-14kg- 1 tablet twice daily; 15-24kg- 2 tablets twice daily; 25-34kg- 3tablets twice daily. AL 80/480mg over 34kg: 1 tablet twice daily for 3 days. Drug Formulation: Tablet Quantity Per Pack: 6 Tablets Place Of Production: Swiss Pharma Nigeria Ltd Marketing Company: SWIPHA Nafdac No: A4-4854